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Pronunciation: a-SEET-a-MIN-oh-fen/pen-TAZ-oh-seen
Generic Name: Acetaminophen/Pentazocine
Brand Name: Generic only. No brands available.

Talacen contains acetaminophen. Severe and sometimes fatal liver problems, including the need for liver transplant, have been reported with the use of acetaminophen. Most cases of these liver problems occurred in patients taking excessive doses of acetaminophen (more than 4,000 mg per day). Also, patients who developed these liver problems were often using more than 1 medicine that contained acetaminophen. Discuss any questions or concerns with your doctor.

Talacen is used for:

Relieving mild to moderate pain.

Talacen is a narcotic and analgesic combination. It works in the brain to reduce pain.

Do NOT use Talacen if: you are allergic to any ingredient in Talacen you have a dependence on opiates (eg, morphine) or you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Talacen:

Some medical conditions may interact with Talacen. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have poor health, low blood oxygen levels, high blood carbon dioxide levels, stomach pain, or severe or persistent diarrhea caused by antibiotic use (pseudomembranous colitis) if you have a history of a recent head injury, growths in the brain (eg, tumors), increased pressure in the brain, or seizures if you have a history of stomach or bowel problems (eg, inflammation, stomach or bowel surgery), lung or breathing problems (eg, asthma, chronic obstructive pulmonary disease [COPD]), liver problems (eg, hepatitis), kidney problems, heart problems (eg, cor pulmonale), a recent heart attack, high blood pressure, the blood disease porphyria, thyroid problems, adrenal gland problems (eg, Addison disease), an enlarged prostate or benign prostatic hypertrophy (BPH), gallbladder problems, inflammation of the pancreas (pancreatitis), urinary blockage or trouble urinating, or curvature of the spine (scoliosis) if you have a history of mental or mood problems, suicidal thoughts or actions, or drug or alcohol abuse or dependence if you are in alcohol withdrawal or if you smoke if you have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the past 14 days

Some MEDICINES MAY INTERACT with Talacen. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticholinergic medicines (eg, oxybutynin, scopolamine) because the risk of severe constipation or trouble urinating may be increased Cimetidine, certain nausea medicines (eg, ondansetron), phenothiazines (eg, chlorpromazine), sodium oxybate (GHB), or other narcotic medicines (eg, oxycodone) because they may increase the risk of Talacen's side effects Anticoagulants (eg, warfarin), MAOIs (eg, phenelzine), or sibutramine because the risk of their side effects may be increased by Talacen Naltrexone or rifamycins (eg, rifampin) because they may decrease the effectiveness of Talacen Methadone or other narcotic medicines (eg, oxycodone) because their effectiveness may be decreased by Talacen Medicines that may harm the liver (eg, methotrexate, ketoconazole, isoniazid, certain medicines for HIV infection) because the risk of liver side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the liver

This may not be a complete list of all interactions that may occur. Ask your health care provider if Talacen may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Talacen:

Use Talacen as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Talacen may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation. If you miss a dose of Talacen and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Talacen.

Important safety information: Talacen may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Talacen. Using Talacen alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks. Avoid drinking alcohol while you are taking Talacen. Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while taking Talacen; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness. Do not change your dose or change how often you take Talacen without checking with your doctor. If you have been taking Talacen for a prolonged period of time, do not stop taking it without checking with your doctor. Tell your doctor or dentist that you take Talacen before you receive any medical or dental care, emergency care, or surgery. Talacen contains acetaminophen. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains acetaminophen. If it does or if you are uncertain, contact your doctor or pharmacist. Talacen may contain sulfites, which can cause allergic reactions in certain individuals (eg, asthma patients). If you have previously had allergic reactions to sulfites, contact your doctor or pharmacist to determine if the medicine you are taking contains sulfites. Talacen may increase your risk of seizures, especially if you have a history of seizures. Contact your doctor right away if you have a seizure while taking Talacen. Talacen may cause constipation. To prevent constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. Talk to your doctor about using fiber laxatives or stool softeners to prevent or treat constipation while you take Talacen. Use Talacen with caution in the ELDERLY; they may be more sensitive to its effects, especially breathing problems, confusion, and hallucinations. Use Talacen with extreme caution in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Talacen, discuss with your doctor the benefits and risks of using Talacen during pregnancy. Talacen is found in breast milk. If you are or will be breast-feeding while you are using Talacen, check with your doctor or pharmacist to discuss the risks to your baby.

When used for long periods of time or at high doses, some people develop a need to continue taking Talacen. This is known as DEPENDENCE or addiction.

If you suddenly stop taking Talacen, you may experience WITHDRAWAL symptoms, including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Possible side effects of Talacen:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; headache; light-headedness; nausea; sweating; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); blistered, red, peeling, or swollen skin; confusion; disorientation; fainting; fast heartbeat; hallucinations; mental or mood changes (eg, depression, exaggerated sense of well-being); seizures; severe or persistent drowsiness, dizziness, light-headedness, or headache; severe stomach pain; slow or shallow breathing; tremor; trouble sleeping; trouble urinating; vision problems (eg, blurred vision); weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Talacen side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include anxiety; burning, numbness, or tingling; confusion; excessive sweating; extreme fatigue; fainting; fast heartbeat; hallucinations; loss of consciousness; nausea; seizures; slow and shallow breathing; symptoms of liver problems (eg, dark urine, loss of appetite, right-sided stomach pain, yellowing of the eyes or skin); unusual bruising or bleeding; unusual drowsiness, dizziness, headache, or light-headedness; unusual thoughts; vomiting.

Proper storage of Talacen:

Store Talacen between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Talacen out of the reach of children and away from pets.

General information: If you have any questions about Talacen, please talk with your doctor, pharmacist, or other health care provider. Talacen is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Talacen. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition Copyright © 2012 Wolters Kluwer Health, Inc. More Talacen resources Talacen Side Effects (in more detail)Talacen Use in Pregnancy & BreastfeedingDrug ImagesTalacen Drug InteractionsTalacen Support Group1 Review for Talacen - Add your own review/rating Talacen Prescribing Information (FDA) Talacen Concise Consumer Information (Cerner Multum) Talacen Advanced Consumer (Micromedex) - Includes Dosage Information Compare Talacen with other medications Pain


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