Rifamycin derivatives


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Rifamycin derivatives


A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Rifamycin derivatives are antibiotics that work by binding to and inhibiting the mycobacterial DNA dependent RNA polymerase. These antibiotics are bacteriocidal and therefore extremely effective antituberculosis agents, but resistance can develop rapidly if used as a single agent. They easily penetrate into cells, body fluids and cerebrospinal fluid so can be used against organisms in the extracellular component and those that may be present in cells such as macrophages. Rifamycin antibiotics should be used throughout the course of tuberculosis treatment, which can be between nine months to a year.

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Medical conditions associated with rifamycin derivatives:

Bartonellosis Endocarditis Haemophilus influenzae Prophylaxis Legionella Pneumonia Leprosy Leprosy, Borderline Leprosy, Tuberculoid Meningitis Meningococcal Meningitis Prophylaxis Mycobacterium avium-intracellulare, Prophylaxis Mycobacterium avium-intracellulare, Treatment Nasal Carriage of Staphylococcus aureus Tuberculosis, Active Tuberculosis, HIV Positive Tuberculosis, Latent Tuberculosis, Prophylaxis Drug List: Rifadin Mycobutin Priftin Rifadin-Iv Rimactane

Rifamycin derivatives

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