Humulin R (Concentrated)

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Pronunciation: IN-su-lin
Generic Name: Insulin Regular
Brand Name: Humulin R (Concentrated)
Humulin R (Concentrated) is used for:

Treating diabetes mellitus.

Humulin R (Concentrated) is a fast-acting form of the hormone insulin. It works by helping your body to use sugar properly. This lowers the amount of glucose in the blood, which helps to treat diabetes.

Do NOT use Humulin R (Concentrated) if: you are allergic to any ingredient in Humulin R (Concentrated) you are having an episode of low blood sugar you are taking an oral diabetes medicine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Humulin R (Concentrated):

Some medical conditions may interact with Humulin R (Concentrated). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you drink alcoholic beverages or smoke if you have kidney or liver problems; nerve problems; adrenal, pituitary, or thyroid problems; or diabetic ketoacidosis if you use 3 or more insulin injections per day if you are fasting, have high blood sodium levels, or are on a low-salt diet

Some MEDICINES MAY INTERACT with Humulin R (Concentrated). Tell your health care provider if you are taking any other medicines, especially any of the following:

Beta-blockers (eg, propranolol), clonidine, guanethidine, lithium, or reserpine because they may increase the risk of high or low blood sugar or may hide the signs and symptoms of low blood sugar, if it occurs Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), disopyramide, fenfluramine, fibrates (eg, clofibrate, gemfibrozil), fluoxetine, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), oral medicines for diabetes (eg, glipizide, metformin, nateglinide), pentamidine, propoxyphene, salicylates (eg, aspirin), somatostatin analogs (eg, octreotide), or sulfonamide antibiotics (eg, sulfamethoxazole) because the risk of low blood sugar may be increased Corticosteroids (eg, prednisone), danazol, diuretics (eg, furosemide, hydrochlorothiazide), estrogen, hormonal contraceptives (eg, birth control pills), isoniazid, niacin, phenothiazines (eg, chlorpromazine), progesterones (eg, medroxyprogesterone), somatropin, sympathomimetics (eg, albuterol, epinephrine, terbutaline), or thyroid hormones (eg, levothyroxine) because they may decrease Humulin R (Concentrated)'s effectiveness, resulting in high blood sugar

This may not be a complete list of all interactions that may occur. Ask your health care provider if Humulin R (Concentrated) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Humulin R (Concentrated):

Use Humulin R (Concentrated) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Humulin R (Concentrated). Talk to your pharmacist if you have questions about this information. Use Humulin R (Concentrated) within 30 to 60 minutes before a meal, as directed by your doctor. If you will be using Humulin R (Concentrated) at home, a health care provider will teach you how to use it. Be sure you understand how to use Humulin R (Concentrated). Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions. Use extreme caution when you measure your dose of Humulin R (Concentrated). Humulin R (Concentrated) contains more insulin per unit than other types of insulin. Accidental overdose may cause serious and sometimes fatal side effects. Humulin R (Concentrated) should be clear and colorless. Do not use Humulin R (Concentrated) if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged. If you are mixing Humulin R (Concentrated) with another insulin, draw Humulin R (Concentrated) into the syringe first. Inject the dose immediately after mixing, as directed by your doctor. Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into a vein or muscle. Injection sites within an injection area (abdomen, thigh, upper arm) must be rotated from one injection to the next. Be sure you have purchased the correct insulin. Insulin comes in a variety of containers, including vials, cartridges, and pens. Make sure that you understand how to properly measure and prepare your dose. If you have any questions about measuring and preparing your dose, contact your doctor or pharmacist for information. Humulin R (Concentrated) begins lowering blood sugar within 30 to 60 minutes after an injection. The effects last up to 4 to 12 hours. Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal. It is very important to follow your insulin regimen exactly. Do NOT miss any doses. Ask your doctor for specific instructions to follow in case you ever miss a dose of insulin.

Ask your health care provider any questions you may have about how to use Humulin R (Concentrated).

Important safety information: Drowsiness, dizziness, lightheadedness, or blurred vision may occur while you use Humulin R (Concentrated). These effects may be worse if you take it with alcohol or certain medicines. Use Humulin R (Concentrated) with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. Do not drink alcohol without discussing it with your doctor. Drinking alcohol may increase the risk of developing high or low blood sugar. Do NOT use more than the recommended dose, use Humulin R (Concentrated) more often than prescribed, or change the type or dose of insulin you are using without checking with your doctor. Any change of insulin should be made cautiously and only under medical supervision. Changes in purity, strength, brand (manufacturer), type (regular, NPH, lente), species (beef, pork, beef-pork, human), and/or method of manufacture may require a change in dose. Illness, especially with nausea and vomiting, may cause your insulin requirements to change. Even if you are not eating, you still require insulin. You and your doctor should establish a sick day plan to use in case of illness. When you are sick, test your blood/urine frequently and call your doctor as instructed. Tell your doctor or dentist that you take Humulin R (Concentrated) before you receive any medical or dental care, emergency care, or surgery. If you will be traveling across time zones, consult your doctor concerning adjustments in your insulin schedule. Carry an ID card at all times that says you have diabetes. An insulin reaction resulting from low blood sugar levels (hypoglycemia) may occur if you take too much insulin, skip a meal, or exercise too much. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart beat faster; make your vision change; give you a headache, chills, or tremors; or make you more hungry. It is a good idea to carry a reliable source of glucose (eg, tablets or gel) to treat low blood sugar. If this is not available, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens. To prevent low blood sugar, eat meals at the same time each day and do not skip meals. Developing a fever or infection, eating significantly more than prescribed, or missing your dose of insulin may cause high blood sugar (hyperglycemia). High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell you doctor right away. Check with your doctor if you notice a depression in the skin or skin thickening at the injection site. You may need to change your injection technique. Proper diet, regular exercise, and regular testing of blood sugar are important for best results when using Humulin R (Concentrated). Lab tests, including fasting blood glucose levels and hemoglobin A1c, may be performed while you use Humulin R (Concentrated). These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Use Humulin R (Concentrated) with caution in the ELDERLY; if low blood sugar occurs, it may be more difficult to recognize in these patients. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Humulin R (Concentrated) while you are pregnant. It is not known if Humulin R (Concentrated) is found in breast milk. If you are or will be breast-feeding while you use Humulin R (Concentrated), check with your doctor. Discuss any possible risks to your baby. Possible side effects of Humulin R (Concentrated):

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Redness, swelling, itching, or mild pain at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; wheezing; muscle pain); changes in vision; chills; confusion; dizziness; drowsiness; fainting; fast or irregular heartbeat; headache; loss of consciousness; mood changes; seizures; slurred speech; swelling; tremor; trouble breathing; trouble concentrating; unusual hunger; unusual sweating; weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Humulin R (Concentrated) side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center or emergency room immediately. Symptoms may include chills; dizziness; drowsiness; fainting; fast or irregular heartbeat; headache; loss of consciousness; nervousness; seizures; shakiness; sweating; tremor; vision changes; weakness.

Proper storage of Humulin R (Concentrated):

Store new (unopened) vials in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Store used (open) vials in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). If refrigeration is not possible, store at room temperature, below 86 degrees F (30 degrees C). Store away from heat and light. If Humulin R (Concentrated) has been frozen or overheated, throw it away. Throw away unrefrigerated or opened vials after 28 days, even if they still contain medicine.

Do not leave Humulin R (Concentrated) in a car on a warm or sunny day. Do not use Humulin R (Concentrated) after the expiration date stamped on the label. Keep Humulin R (Concentrated), as well as syringes and needles, out of the reach of children and away from pets. If Humulin R (Concentrated) has been mixed with other medicines or diluted, you may need to store it differently. Ask your doctor, pharmacist, or health care provider how to store Humulin R (Concentrated).

General information: If you have any questions about Humulin R (Concentrated), please talk with your doctor, pharmacist, or other health care provider. Humulin R (Concentrated) is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Humulin R (Concentrated). If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Humulin R (Concentrated) resources Humulin R (Concentrated) Side Effects (in more detail)Humulin R (Concentrated) Use in Pregnancy & BreastfeedingHumulin R (Concentrated) Drug InteractionsHumulin R (Concentrated) Support Group0 Reviews for Humulin R (Concentrated) - Add your own review/rating Humulin R (Concentrated) U-500 Concise Consumer Information (Cerner Multum) Humulin R Concise Consumer Information (Cerner Multum) Humulin R Prescribing Information (FDA) Iletin II Regular Pork Concise Consumer Information (Cerner Multum) Novolin R Prescribing Information (FDA) Compare Humulin R (Concentrated) with other medications Diabetes, Type 1Diabetes, Type 2Diabetic KetoacidosisGestational DiabetesGrowth Hormone Reserve TestHyperkalemiaInsulin Resistance SyndromeNonketotic Hyperosmolar Syndrome

Humulin R Concentrated

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