Diurexan 20mg Tablets


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Diurexan 20mg Tablets


Diurexan 20 mg tablets


Read all of this leaflet carefully before you start taking this medicine. Keep this leaflet. You may need to read it again. If you have any further questions, ask your doctor or pharmacist. This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. In this leaflet: 1. What Diurexan is for 2. Before you take Diurexan 3. How to take Diurexan 4. Possible side effects 5. How to store Diurexan 6. Further information What Diurexan is for

Diurexan belongs to the group of medicines known as diuretics. Diuretics are often referred to as water tablets.

Diurexan removes excess water from the body by increasing how often you urinate. It is used to treat high blood pressure (hypertension) and too much fluid in the body (oedema), often caused by heart failure or problems with your liver or kidneys.

Before you use Diurexan Do not take Diurexan if: You are allergic to Xipamide You are allergic to any of the other ingredients of Diurexan (listed in section 6) You have low levels of salts in your blood sometimes caused by severe vomiting or diarrhoea You have liver disease that is causing you to become unconscious You have severe kidney disease You have untreated Addison’s disease – a condition in which your adrenal glands do not produce sufficient levels of natural steroid in the blood You are less than 4 months’ pregnant.

If any of the above applies to you, talk to your doctor or pharmacist.

Check with your doctor before taking Diurexan if: You have gout or have too much uric acid in your urine You have diabetes You have kidney or liver disease You have an enlarged prostate gland or trouble urinating You suffer with coronary or cerebral arteriosclerosis (narrowing of the arteries in the heart or brain) Your body produces too much aldosterone, a hormone which controls salt and water balance (hyperaldosteronism) You have diarrhoea You are malnourished (a severe lack of food) You are being sick You are over 65 years of age. Tell your doctor if you are taking any of the following medicines: Medicines for high blood pressure Medicines called cardiac glycosides such as digoxin for heart problems Insulin or tablets for diabetes Lithium.

Taking these Diurexan at the same time as these medicines may lead to your doctor adjusting the dose you require.

Also tell your doctor if you are taking:

Steroids used to treat many conditions including asthma, arthritis, eczema and dermatitis ACTH which is mainly used to test if your pituitary gland is working properly Carbenoxolone used to treat stomach ulcers and inflammation of the oesophagus Amphotericin used to treat fungal and bacterial infections Laxatives.

These medicines may cause the level of potassium in your blood to fall when used at the same time as Diurexan.

Tell your doctor or pharmacist if you are taking any other medicines, including medicines obtained without a prescription.

Pregnancy and breast-feeding

If you are pregnant, trying to become pregnant or breastfeeding ask your doctor or pharmacist for advice before taking Diurexan.

How to take Diurexan

Always take Diurexan exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.


Your doctor will choose the dose that is right for you. Your dose will be shown clearly on the label that your pharmacist puts on your medicine. If it does not, or you are not sure, ask your doctor or pharmacist.

For high blood pressure:

The usual dose is one tablet per day, taken early in the morning.

For excessive fluid retention:

The usual starting dose is two tablets per day, taken early in the morning.

Once your doctor has seen how the medicine is working, they may change your dose. They may reduce it to one tablet per day. If the medicine is not having much effect, your doctor may increase your dose to 3 or 4 tablets per day.

Medical check-ups

Taking Diurexan for a long time can cause you to lose potassium from your blood. Your doctor will check for this and may prescribe you extra potassium especially if you are elderly or getting little potassium in your diet.

If you take more Diurexan than you should

If you accidentally take too much Diurexan immediately go to the nearest hospital casaulty department or your doctor. An overdose may cause the loss of too much fluid from your body.

This can cause hypotension, making you feel faint and change the make-up of your blood.

You may have your stomach washed out and an infusion into your vein to replace lost fluids.

If you forget to take Diurexan

Do not take a double dose to make up for a missed dose. Simply take your dose as planned.

If you have any further questions on the use of this product, ask your doctor or pharmacist

Possible side effects

Like all medicines, Diurexan can cause side effects, although not everybody gets them.

These may include:

Slight dizziness Effects on your stomach or intestine such as stomach pain, constipation and diarrhoea Low potassium and sodium levels in blood (hypokalaemia and hyponatraemia respectively) which may cause headaches, muscle cramps and weakness.

If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

How to store Diurexan

Keep out of the reach and sight of children.

Do not use Diurexan after the expiry date which is stated on the carton. The expiry date refers to the last day of that month.

Medicines should not be disposed of via wastewater or household waste. Return any medicine you no longer need to your pharmacist.

Further information What Diurexan contains

The active substance is xipamide. Each tablet contains 20 mg of xipamide.

The other ingredients are maize starch, mannitol, cellulose powder, colloidal silicon dioxide, magnesium stearate and purified water.

What Diurexan looks like

Diurexan tablets are white and round with a notch on one side and an "A" on the other. They are about 6 mm in diameter. They come in blister strips strips of 14 tablets with 10 blister strips in a box.

Marketing Authorisation Holder is: Meda Pharmaceuticals Ltd Skyway House Parsonage Road Takeley Bishop’s Stortford CM22 6PU United Kingdom Manufacturer is: Sidefarma, S.A. Rua da Guin?, n? 26 2689-514 Prior Velho PORTUGAL

This leaflet was last updated on September 2008

If this leaflet is difficult to see or read and you would like it in a different format, please contact

Meda Pharmaceuticals Skyway House Parsonage Road Takeley Bishop’s Stortford CM22 6PU United Kingdom

Diurexan 20mg Tablets

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