sodium chloride

Generic Name: sodium chloride (oral) (SOE dee um KLOR ide)
Brand Names: Sodium Chloride

What is sodium chloride?

Sodium chloride is the chemical name for salt. Sodium is an electrolyte that regulates the amount of water in your body. Sodium also plays a part in nerve impulses and muscle contractions.

Sodium chloride is used to treat or prevent sodium loss caused by dehydration, excessive sweating, or other causes.

Sodium chloride may also be used for purposes not listed in this medication guide.

What is the most important information I should know about sodium chloride? You should not take sodium chloride if you have ever had an allergic reaction to it, or if you have high sodium levels in your blood.

Before you take sodium chloride, tell your doctor if you have high blood pressure, kidney or liver disease, fluid retention (especially around your legs or your lungs), congestive heart failure, preeclampsia of pregnancy if you are on a low-salt diet, or if you are allergic to any foods or drugs.

Tell your doctor if you are pregnant or breast-feeding. Stop using sodium chloride and call your doctor at once if you have stomach pain, nausea and vomiting, or swelling in your hands or feet.

Call your doctor if your symptoms do not improve, or if they get worse while using sodium chloride.

What should I discuss with my health care provider before taking sodium chloride? You should not take sodium chloride if you have ever had an allergic reaction to it, or if you have high sodium levels in your blood.

To make sure you can safely take sodium chloride, tell your doctor if you have any of these other conditions:

high blood pressure;

kidney disease;

liver disease (especially cirrhosis);

a buildup of fluid around your lungs (also called pleural effusion);

fluid retention (especially swelling in your ankles or feet );

congestive heart failure;

if you are pregnant and you have high blood pressure and fluid retention (also called preeclampsia);

if you are allergic to any foods or drugs; or

if you are on a low-salt diet.

FDA pregnancy category C. It is not known whether sodium chloride will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether sodium chloride passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How should I take sodium chloride?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take this medicine with a full glass (8 ounces) of water.

Sodium chloride may be taken with or without food.

To be sure this medication is helping your condition, your blood may need to be tested often. Visit your doctor regularly.

Do not share this medication with another person, even if they have the same symptoms you have.

Call your doctor if your symptoms do not improve, or if they get worse while using sodium chloride.

Store at room temperature away from moisture, heat, and light. What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, stomach cramps, diarrhea, fast or uneven heart rate, weakness, swelling in your hands or feet, feeling restless or irritable, slow breathing, feeling short of breath, or seizure (convulsions).

What should I avoid while taking sodium chloride?

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Sodium chloride side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using sodium chloride and call your doctor at once if you have a serious side effect such as:

nausea and vomiting;

stomach pain; or

swelling in your hands, ankles, or feet.

Less serious side effects are more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect sodium chloride?

There may be other drugs that can interact with sodium chloride. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Sodium Chloride resources Sodium Chloride Drug Interactions Sodium Chloride Support Group 0 Reviews for Sodium Chloride - Add your own review/rating Compare Sodium Chloride with other medications Postural Orthostatic Tachycardia Syndrome Where can I get more information? Your pharmacist can provide more information about sodium chloride.

Read More:

Minims Saline

Minims*

Saline

0.9% w/v Sodium Chloride

About Minims Saline

The name of this product is Minims Saline. Each Minims unit contains 0.9% w/v Sodium Chloride eye drops, solution. It also contains purified water. Each Minims unit is a sterile, single-use eye drop containing 0.5ml of solution.

Who makes Minims Saline ?

Minims Saline are manufactured by

Laboratoire Chauvin S.A. ZI Ripotier 07200/Aubenas France

The Marketing Authorisations for Minims Saline (PL0033/5017R and PA 118/20/1) are held by

Chauvin Pharmaceuticals Ltd. 106 London Road Kingston-Upon-Thames KT2 6TN England What is it for ?

Sodium chloride solution is used to irrigate (wash out) the eyes.

Before using Minims Saline

They are no special precautions which should be taken before using this product.

Using Minims Saline

The amount of solution used should be enough to irrigate the eye properly.

If you are putting in your own drops then following these instructions carefully.

1. Wash hands thoroughly. Peel the overwrap apart and take out the Minims unit. 2. Twist off the cap. 3. Look upwards and gently pull down the lower eyelid. 4. Hold the Minims unit just above your eye and gently squeeze until some liquid falls into the gap between your eyeball and lower eyelid. 5. Release the lower eyelid. 6. Throw away the Minims unit when you have finished. After using Minims Saline

No side effects are expected to occur following the use of these eye drops, however, if you do suddenly feel unwell after using these eye drops then contact your doctor or the nearest casualty department.

Storing Minims Saline Minims Saline should be stored below 25°C and in original container to protect from light. Do not allow it to freeze. The expiry date is printed on each Minims unit overwrap and on the carton label. Do not use them after this date.

This leaflet applies only to Minims Saline but it does not contain all the information known about this eye drop. If you have any questions or are not sure of anything, ask your doctor or pharmacist.

Date of Preparation : February 2002.

Date of Partial Revision : January 2004.

* Trade Mark

Chauvin Pharmaceuticals Ltd. 106 London Road Kingston-Upon-Thames KT2 6TN England Tel :020 8781 2900 Fax :020 8781 2901

Read More:

Alkalosis Medications

Definition of Alkalosis: Alkalosis is a condition of excess base (alkali) in the body fluids. This is the opposite of excess acid (acidosis), and can be caused by many different conditions.

Drugs (by generic name) associated with Alkalosis

The following drugs and medications are in some way related to, or used in the treatment of Alkalosis. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

Learn more about Alkalosis

Medical Encyclopedia:

Alkalosis
Drug List: Ammonium-Chloride

Read More:

Magnesium Chloride Injection

Magnesium Chloride Injection
200 mg/mL (20% w/v)
2.951 mOsmol/mL

Rx Only

DESCRIPTION

Magnesium Chloride Injection is a sterile solution of Magnesium Chloride Hexahydrate in Water for Injection q.s. Each mL contains: Magnesium Chloride Hexahydrate 200 mg, Sodium Chloride 9 mg, Benzyl Alcohol 1% as a preservative, Water for Injection, q.s. pH adjusted with Hydrochloric Acid and/or Sodium Hydroxide. Total osmolarity equivalent to 2951 mOsmol/L. Contains 1.97 mEq of Mg++ and Cl? per mL.

The structural formula is MgCl2•6H2O

ACTIONS

Magnesium is the second most plentiful cation within cellular fluids. It is an important activator of many enzyme systems, and deficits are accompanied by a variety of functional disturbances.

INDICATIONS AND USAGE

As an electrolyte replenisher in magnesium deficiencies.

CONTRAINDICATIONS

Magnesium Chloride Injection should not be administered if there is renal impairment, marked myocardial disease or to comatose patients.

WARNINGS

Do not use if a precipitate is present.

This product contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum.

Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity. Tissue loading may occur at even lower rates of administration.

PRECAUTIONS

The usual precautions for parenteral administration should be observed.  Administer with caution if flushing and sweating occurs. A preparation of a calcium salt should be readily available for intravenous injection to counteract potential serious signs of magnesium intoxication. As long as deep tendon reflexes are active it is probable that the patient will not develop respiratory paralysis. Respiration and blood pressure should be carefully observed during and after administration of Magnesium Chloride Injection.

Pregnancy Teratogenic Effects

Pregnancy Category C. Animal reproduction studies have not been conducted with magnesium chloride. It is also not known whether magnesium chloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Magnesium chloride should be given to a pregnant woman only if clearly needed.

ADVERSE REACTIONS

Flushing, sweating, sharply lowered blood pressure, hypothermia, stupor, and ultimately respiratory depression.

DOSAGE AND ADMINISTRATION

For intravenous infusion: 4 grams in 250 mL of 5% Dextrose Injection, at a rate not exceeding 3 mL per minute. Serum magnesium levels should serve as a guide to continued dosage.

USUAL DOSAGE RANGE: 1 to 40 grams daily.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.

HOW SUPPLIED

Magnesium Chloride Injection 200 mg/mL (20% w/v)

NDC 0517-5034-01     50 mL Multiple Dose Vial     Individually boxed

Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) (See USP Controlled Room Temperature).

AMERICAN
REGENT, INC.
SHIRLEY, NY 11967

IN5034

Rev. 1/09

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

PRINCIPAL DISPLAY PANEL – 50 mL Container

NDC 0517-5034-01

MAGNESIUM
CHLORIDE
INJECTION

200 mg/mL
(20% w/v)
2.951 mOsmol/mL

50 mL
MULTIPLE DOSE VIAL

Rx Only

AMERICAN REGENT, INC.
SHIRLEY, NY 11967

MAGNESIUM CHLORIDE 
magnesium chloride  injection, solution Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0517-5034 Route of Administration INTRAVENOUS DEA Schedule      Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength MAGNESIUM CHLORIDE (MAGNESIUM) MAGNESIUM CHLORIDE 200 mg  in 1 mL Inactive Ingredients Ingredient Name Strength SODIUM CHLORIDE 9 mg  in 1 mL BENZYL ALCOHOL   HYDROCHLORIC ACID   SODIUM HYDROXIDE   WATER   Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains          Packaging # NDC Package Description Multilevel Packaging 1 0517-5034-01 1 VIAL In 1 CARTON contains a VIAL, MULTI-DOSE 1 50 mL In 1 VIAL, MULTI-DOSE This package is contained within the CARTON (0517-5034-01)
Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date Unapproved drug other 09/30/1990
Labeler - American Regent, Inc. (622781813) Revised: 10/2011American Regent, Inc. More Magnesium Chloride Injection resources Magnesium Chloride Injection Side Effects (in more detail) Magnesium Chloride Injection Use in Pregnancy & Breastfeeding Magnesium Chloride Injection Drug Interactions Magnesium Chloride Injection Support Group 0 Reviews for Magnesium Chloride Injection - Add your own review/rating Compare Magnesium Chloride Injection with other medications Heart Attack Hypomagnesemia

Read More:

Hyper-Sal inhalation

Generic Name: sodium chloride (inhalation) (SOE dee um KLOR ide)
Brand Names: Broncho Saline, Hyper-Sal, Sodium Chloride, Inhalation

What is Hyper-Sal (sodium chloride (inhalation))?

Sodium chloride is the chemical name for salt. Sodium chloride can reduce some types of bacteria in certain body secretions, such as saliva.

Sodium chloride inhalation is used to produce sputum (mucus, or phlegm) from the mouth in order to collect it for medical testing. This medication may also be used to dilute other medications inhaled through a nebulizer.

Sodium chloride inhalation may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Hyper-Sal (sodium chloride (inhalation))?

Before using sodium chloride inhalation, tell your doctor if you have asthma, congestive heart failure, heart disease, high blood pressure, epilepsy, kidney or liver disease, migraine headaches, any type of edema (swelling), if you have recently had surgery, or if you are on a low-salt diet.

Tell your doctor about all other medications you use, especially potassium supplements, diuretics, steroids, blood pressure medications, or medications that contain sodium (such as Alka-Seltzer or Zegrid).

Tell your caregivers at once if you have a serious side effect such as chest pain, trouble breathing, swelling in your hands or feet, feeling like you might pass out, tired feeling, muscle twitching, confusion, uneven heart rate, extreme thirst, increased or decreased urination, leg discomfort, muscle weakness or limp feeling. What should I discuss with my health care provider before using Hyper-Sal (sodium chloride (inhalation))? You should not use this medication if you have ever had an allergic reaction to sodium chloride inhalation.

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before using sodium chloride inhalation, tell your doctor if you have:

asthma;

congestive heart failure;

heart disease or high blood pressure;

epilepsy;

kidney or liver disease;

migraine headaches;

any type of edema (swelling);

if you have recently had surgery; or

if you are on a low-salt diet.

FDA pregnancy category C. It is not known whether sodium chloride inhalation is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether sodium chloride inhalation passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How is sodium chloride inhalation given?

Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Sodium chloride inhalation is given using a nebulizer. You will inhale the medication through a face mask, mouth piece, or other device connected to the nebulizer.

Your doctor, nurse, or other healthcare provider can show you how to properly use the nebulizer.

Sodium chloride is a liquid that is placed into the medication chamber of the nebulizer. A mouthpiece or face mask is then attached to the drug chamber, along with an air compressor.

To prepare for inhaling sodium chloride through a nebulizer, you may be given another inhaled medication to prevent bronchospasm (muscle contractions within the airways of the lungs). Your doctor may also ask you to blow your nose, rinse your mouth with water, or wipe the inside of your mouth with a tissue. Follow your doctor's instructions carefully for best results.

In most cases, you will use this medication while you are sitting upright in a comfortable position. Breathe slowly and evenly while you are using the mask, mouthpiece, or other breathing device. You may also be given a nose clip to wear that will close your nasal passages so that you inhale only through your mouth.

If you are using this medication as part of a sputum test, you will need to spit about every 5 minutes or as directed by your healthcare provider. Cough deeply from your chest to produce an optimal specimen for testing.

Continue breathing through the nebulizer for as long as directed by your doctor. Once you have completed the inhalation for the prescribed amount of time, throw away any liquid that is left in the medicine chamber. Do not save it for later use.

If you store sodium chloride at home, keep it at room temperature away from moisture and heat. What happens if I miss a dose?

Since sodium chloride inhalation is sometimes used only as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose? Tell your caregivers at once if you think you have used too much of this medicine.

Overdose symptoms may include increased thirst, drowsiness, restless feeling, confusion, muscle pain or weakness, nausea, vomiting, increased urination, fast heart rate, fainting, and seizure (convulsions).

What should I avoid after receiving Hyper-Sal (sodium chloride (inhalation))?

Follow your doctor's instructions about any restrictions on food, beverages, or activity after using sodium chloride inhalation.

Hyper-Sal (sodium chloride (inhalation)) side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Tell your caregivers at once if you have a serious side effect such as:

chest pain, trouble breathing;

feeling like you might pass out;

swelling in your hands or feet;

tired feeling, muscle twitching;

confusion, uneven heart rate, extreme thirst, increased or decreased urination, leg discomfort, muscle weakness or limp feeling.

Less serious side effects may include a salty taste or slight burning or irritation in your mouth.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Hyper-Sal (sodium chloride (inhalation))?

Tell your doctor about all other medications you use, especially:

potassium supplements;

a diuretic (water pill);

a steroid such as prednisone, fluticasone (Advair), mometasone (Asmanex, Nasonex), dexamethasone (Decadron, Hexadrol) and others;

blood pressure medications; or

medications that contain sodium, such as Alka-Seltzer or Zegrid (omeprazole and sodium bicarbonate).

This list is not complete and there may be other drugs that can interact with sodium chloride inhalation. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Hyper-Sal resources Hyper-Sal Drug Interactions Hyper-Sal Support Group 0 Reviews · Be the first to review/rate this drug Where can I get more information? Your doctor or pharmacist can provide more information about sodium chloride inhalation.

Read More:

Barbiturates

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Barbiturates are a group of drugs derived from barbituric acid. They suppress central nervous system activity and are effective anxiolytics, antiepileptics, sedatives and hypnotics. Barbiturates enhance the action of GABA by binding to the GABA-receptor/chloride channel.

They are classified into three groups according to their duration of action

See also

Medical conditions associated with barbiturates:

Epilepsy Hyperbilirubinemia Insomnia Light Sedation Sedation Seizures Status Epilepticus Drug List: Seconal Seconal-Sodium Mebaral Nembutal-Sodium Luminal Butisol-Sodium Nembutal Solfoton

Read More:

Sterile Potassium Chloride Concentrate 15% (hameln)

Read all of this leaflet carefully before you start taking this medicine. Keep this leaflet. You may need to read it again. If you have further questions, please ask your doctor or your pharmacist. This medicine has been prescribed for you personally and you should not pass it on to others. It may harm them, even if their symptoms are the same as yours. In this leaflet: 1. What your medicine is and what it is used for 2. Before you receive it 3. How it is administered 4. Possible side effects 5. Storing your injection 6. Use by date Sterile Potassium Chloride Concentrate 15%

Each ml contains 0.15 g potassium chloride in a sterile solution for injection. The other ingredients are hydrochloric acid and water for injections.

Holder of the Marketing Authorisation: hameln pharmaceuticals ltd Gloucester United Kingdom Manufacturer: hameln Pharmaceuticals gmbh Langes Feld 13 31789 Hameln Germany What potassium chloride is and what it is used for

Potassium chloride occurs naturally in your body.

It is used to replace the loss of potassium from your body, if this cannot be achieved when given by mouth or in the diet.

The injection is supplied in clear glass ampoules containing 10 ml.

10 ampoules are supplied in each carton.

Before the injection is given to you

Please tell your doctor, nurse or pharmacist before being given the injection if you:

suffer from impaired kidney function suffer from Addison's disease (a disease characterised by a reduced secretion of hormones from a gland situated near the kidneys) are very dehydrated suffer from heat cramps suffer from disturbances in the salt content of your blood are pregnant or breast-feeding

Please inform your doctor, nurse or pharmacist if you are taking or have recently taken any other medicines, even those not prescribed, especially diuretics (water tablets) as these may interfere with this injection.

How the injection is given to you

Your doctor, nurse or pharmacist will give you the injection.

Sterile Potassium Chloride Concentrate 15% may be given by an intravenous injection (into a vein).

In emergencies, it may be necessary to give the injection without your knowledge.

Your doctor will decide on the correct dosage for you and when or how the injection will be given.

The injection must be diluted at least 50 times before it is given to you.

Possible side effects

Like all medicines, potassium chloride can have side effects.

Potassium chloride may cause the following side effects:

pain at the site of injection inflammation of the vein into which the solution is being injected raised blood levels of potassium

If you experience these or any other side effects not mentioned in this leaflet, please inform your doctor, nurse or pharmacist

Storing your injection

Your injection will be stored under 25°C, protected from light and out of the reach and sight of children.

Use by date

The doctor, nurse or pharmacist will check that the injection is not past its expiry date before giving you the injection.

This leaflet was last updated on March 25th 2004.

PL01502/0007R

43856/19/04

Read More:

Organophosphate Poisoning Medications

Drugs associated with Organophosphate Poisoning

The following drugs and medications are in some way related to, or used in the treatment of Organophosphate Poisoning. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

Topics under Organophosphate Poisoning Gulf War Syndrome (0 drugs)
Drug List: Atnaa Duodote Protopam-Chloride

Read More:

Boots Antiseptic Gel

Boots Antiseptic Gel

(Cetylpyridinium Chloride)

Prevents Infection Helps Healing Process Effective Cleansing Action

e 30 g

Read all of this carton for full instructions.

What this medicine is for

This medicine contains Cetylpyridinium Chloride which belongs to a group of medicines called antiseptics, which act to prevent infection.

It can be used on cuts, grazes, insect bites, minor wounds, spots, minor burns and scalds.

Before you use this medicine

Do not use:

If you are allergic to any of the ingredients On weeping or badly inflamed skin Frequently or for long periods of time (you may become sensitive to the medicine)

You can use this medicine if you are pregnant or breastfeeding.

How to use this medicine

Check the seal is not broken before first use. If it is, do not use the gel.

Apply to the skin only.

Avoid contact with the eyes.

Children and adults:

Apply to the affected area of skin 2 or 3 times a day.

Do not use more than the amount recommended above.

If the skin does not appear to heal talk to your doctor.

If anyone accidentally swallows some:

Talk to a doctor straight away.

Possible side effects

Most people will not have problems, but some may get some.

If you get any of these side effects, stop using the gel and see a doctor:

Allergic reaction (e.g. skin rash, red or itchy skin)

These other effects are less serious. If they bother you talk to a pharmacist:

Skin irritation

If any side effect becomes severe, or you notice any side effect not listed here, please tell your pharmacist or doctor.

Keep all medicines out of the sight and reach of children.

Use by the date on the end flap of the carton.

Active ingredient

This gel contains Cetylpyridinium Chloride 0.025% w/w.

Also contains: purified water, glycerol, hypromellose, sodium citrate, citric acid.

PL 00014/0556

Text prepared 3/07

Manufactured by the Marketing Authorisation holder The Boots Company PLC Nottingham NG2 3AA

If you need more advice ask your pharmacist.

BTC14517 vD 12-12-07

Read More:

Jasimenth

Jasimenth may be available in the countries listed below.

Ingredient matches for Jasimenth Ascorbic Acid

Ascorbic Acid is reported as an ingredient of Jasimenth in the following countries:

Germany Dequalinium Chloride

Dequalinium Chloride is reported as an ingredient of Jasimenth in the following countries:

Germany

International Drug Name Search

Read More:

Luborant

1. Name Of The Medicinal Product

Luborant.

2. Qualitative And Quantitative Composition

Each 0.8ml contains 0.003mg of Sodium Fluoride BP

Nipasept Sodium 1.600mg per 0.8 ml contains mixture of sodium hydroxybenzoates which is comprised of sodium p-hydroxybenzoate max. 0.064mg, Sodium Methyl 4-Hydroxybenzoate (E 219) 1.088mg to 1.216mg per 0.8 ml; Sodium Ethyl 4-hydroxybenzoate (E 215) 0.208mg to 0.288mg per 0.8 ml and Sodium Propyl 4-hydroxybenzoate (E 217) 0.128mg to 0.208mg.

3. Pharmaceutical Form

Oromucosal solution.

Pink viscous liquid with as odour of orange.

4. Clinical Particulars 4.1 Therapeutic Indications

Saliva deficiency. Luborant is a saliva substitute for the management of conditions involving dryness of the mouth. These include xerostomia following radiotherapy or during treatment with antidepressants or anxiolytics, and other conditions involving a decrease in production of saliva, such as Sjogren's disease.

4.2 Posology And Method Of Administration

Luborant is for oral use.

Adults, including the elderly: Two or three single applications orally up to four times daily or as directed by the physician. The average dose per application is 0.8ml of the product.

4.3 Contraindications

Hypersensitivity to sodium fluoride.

4.4 Special Warnings And Precautions For Use

Mottling of dental enamel has occurred in association with use of Sodium Fluoride in larger amounts than those contained in the dosage recommended for Luborant.

Do not exceed the stated dose.

The contents should be discarded if not used before a date one month after the date of opening.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

None known.

4.6 Pregnancy And Lactation

There is no known or perceived hazard for use in pregnancy or lactation at the dosage recommended.

4.7 Effects On Ability To Drive And Use Machines

None.

4.8 Undesirable Effects

None stated

4.9 Overdose

There are no reports of overdose. Serious symptoms are unlikely following acute overdosage.

5. Pharmacological Properties 5.1 Pharmacodynamic Properties

Potassium Chloride

]

Salts normally found in saliva Electrolyte concentration close to whole saliva. No precise pharmacological activity other than electrolyte replacement in oral cavity.

Magnesium Chloride

]

 

hexahydrate

 

 

Calcium Chloride dihydrate

]

 

Potassium Phosphate Dibasic

]

 

Potassium Phosphate Monobasic

]

 

Sodium fluoride: used for the prophylaxis of dental caries, it renders the dentine and enamel of the teeth more resistant to acid.

5.2 Pharmacokinetic Properties

Luborant is applied topically to the oral mucous membrane for its local effects within the oral cavity. Although the individual constituent salts may undergo gastro-intestinal absorption, their concentration in daily dosage recommended for Luborant represents only a small percentage pf the recommended daily human requirements of these salts and can not, therefore, be expected to influence normal fluid or electrolyte balance.

5.3 Preclinical Safety Data

No further relevant information other than that which is included in other sections of the Summary of Product Characteristics.

6. Pharmaceutical Particulars 6.1 List Of Excipients

Potassium Chloride

Magnesium Chloride hexahydrate

Calcium Chloride dihydrate

Potassium Phosphate Dibasic

Potassium Phosphate Monobasic

Nipasept Sodium

Sorbitol solution 70% Non-crystallizing

Sodium carboxymethyl cellulose

Orange Flavour IFF VX 1997

Carmoisine Red CI 14720 E122

Hydrochloric Acid

Purified Water

6.2 Incompatibilities

None known.

6.3 Shelf Life

Unopened : 2 years

Opened : 1 month

6.4 Special Precautions For Storage

Keep in outer carton.

Do not store above 25°C.

6.5 Nature And Contents Of Container

60ml, high density polyethylene bottle with a pump action applicator packed in cardboard cartons to contain 1 x 60ml and 6 x 60ml bottles.

6.6 Special Precautions For Disposal And Other Handling

Contents to be discarded if not used before a date one month after the date of opening.

7. Marketing Authorisation Holder

Goldshield Pharmaceuticals Limited,

NLA Tower, 12-16 Addiscombe road,

Croydon,

Surrey,

CR0 0XT,

United Kingdom

8. Marketing Authorisation Number(S)

PL 12762/0227

9. Date Of First Authorisation/Renewal Of The Authorisation

10th January 1990/24th February 1999

10. Date Of Revision Of The Text

December 2009

Read More:

Dettol Antiseptic Wash

1. Name Of The Medicinal Product

Dettol Antiseptic Wash.

2. Qualitative And Quantitative Composition Active Constituent % w/v Benzalkonium chloride 0.198 3. Pharmaceutical Form

Topical Spray.

4. Clinical Particulars 4.1 Therapeutic Indications

For the antiseptic cleansing of minor wounds such as cuts and skin grazes, insect bites and stings, small burns and scalds.

4.2 Posology And Method Of Administration

For adults and children: Spray onto the wound until it is visibly wet and clean, and any dirt and debris has been washed away. If necessary use a clean tissue or cotton wool to wipe up any excess liquid. Repeat as necessary.

4.3 Contraindications

None known.

4.4 Special Warnings And Precautions For Use

Label Warning: For external use only. Do not use around the eyes or ears, in the mouth or over large areas of the body. Do not inhale. In the case of accidental eye contact, the eye should be irrigated with copious amounts of cold water.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

None known.

4.6 Pregnancy And Lactation

Can be used.

4.7 Effects On Ability To Drive And Use Machines

None known.

4.8 Undesirable Effects

None known.

4.9 Overdose

Not applicable.

5. Pharmacological Properties 5.1 Pharmacodynamic Properties

Benzalkonium chloride is a quaternary ammonium compound which has been used for many years as a surfactant and antiseptic/disinfectant. It is known to be bactericidal in low concentrations to a wide range of Gram-positive and Gram-negative bacteria.

5.2 Pharmacokinetic Properties

Quaternary ammonium compounds such as benzalkonium chloride are only absorbed to a very small extent through human skin.

5.3 Preclinical Safety Data

The low level of benzalkonium chloride in the product, coupled with its low level of absorption from intact and broken skin, make it unlikely that any significant systemic toxic effects would arise from its use. There is evidence that it can have an irritant effect on mucous membranes.

6. Pharmaceutical Particulars 6.1 List Of Excipients

The product contains the following excipients:

Propylene glycol

Sodium acid phosphate

Sodium phosphate

Mild pine perfume

Disodium edetate

Softened water

6.2 Incompatibilities

Benzalkonium chloride may be deactivated when used with soap or other surfactants.

6.3 Shelf Life

Two years at 30°C.

6.4 Special Precautions For Storage

Store below 30°C.

6.5 Nature And Contents Of Container

The liquid is contained in a natural HDPE container with a finger action spray pump for administration. The pump head is protected by a clear, polypropylene co-polymer overcap. The pack size is 100 ml.

6.6 Special Precautions For Disposal And Other Handling

Not applicable.

7. Marketing Authorisation Holder

Reckitt Benckiser (UK) Limited

103-105 Bath Road

Slough, SL1 3UH

United Kingdom

8. Marketing Authorisation Number(S)

PL 19718/0003

9. Date Of First Authorisation/Renewal Of The Authorisation

4 November 2002

10. Date Of Revision Of The Text

22/11/2010

Read More:

Sodium Cromoglicate 2% wv Eye Drops (POM)

1. Name Of The Medicinal Product

Sodium Cromoglicate 2% w/v Eye Drops

2. Qualitative And Quantitative Composition

Sodium Cromoglicate 2% w/v

3. Pharmaceutical Form

Eye drops, solution.

A clear, colourless solution.

4. Clinical Particulars 4.1 Therapeutic Indications

The prevention and treatment of acute, seasonal and perennial allergic conjunctivitis.

4.2 Posology And Method Of Administration

Adults, Elderly & Children : One or two drops into each eye up to four times a day.

4.3 Contraindications

Patients with known hypersensitivity to any of the ingredients.

4.4 Special Warnings And Precautions For Use

This formulation of Sodium Cromoglicate Eye Drops contains benzalkonium chloride as a preservative. Benzalkonium chloride may be deposited in soft contact lenses. Hence, Sodium Cromoglicate Eye Drops should not be used while wearing these lenses. The lenses should be removed before instillation of the drops and not reinserted earlier than 15 minutes after use.

Patients should also be instructed that ocular solutions, if handled improperly can become contaminated by common bacteria known to cause ocular infections. Serious damage to the eye and subsequent loss of vision may result from using contaminated solutions. Patients should also be advised that if they develop any intercurrent ocular condition (e.g. trauma, ocular surgery or infection), they should immediately seek their physician's advice concerning the continued use of present multi-dose container. There have been reports of bacterial keratitis associated with the use of topical ophthalmic products.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

None known

4.6 Pregnancy And Lactation

There are no adequeate and well-controlled studies of Sodium Cromoglicate eye drops in pregnant women. Therefore, use during pregnancy is not recommended unless the benefit outweighs the potential risk.

It is not known whether Sodium Cromoglicate is excreted in human milk. Therefore caution should be exercised when the eye drops are administered to nursing mothers.

4.7 Effects On Ability To Drive And Use Machines

Transient stinging or blurring of vision may occur on instillation of the drops.

Do not drive or use machinery until normal vision is restored.

4.8 Undesirable Effects

Transient stinging and burning on instillation of the drops. Rarely, other symptoms of local irritation.

4.9 Overdose

Medical observation is recommended in cases of overdosage.

Sodium cromoglicate is poorly absorbed both from the eye and from the gastrointestinal tract.

5. Pharmacological Properties 5.1 Pharmacodynamic Properties

Sodium cromoglicate inhibits the degranulation of sensitised mast cells which normally occurs after exposure to allergens and thereby prevents the release of allergic mediators such as histamine.

5.2 Pharmacokinetic Properties

Sodium cromoglicate is poorly absorbed from the eye (approximately 0.03% in healthy volunteers) due to its lipid insolubility. Orally, it is poorly absorbed from the gastrointestinal tract with a reported bioavailability of 1%. Systemically, sodium cromoglicate is excreted unchanged in the bile and urine.

Trace amounts have been detected in the aqueous humour of rabbit eyes up to 24 hours after administration.

5.3 Preclinical Safety Data

Pre-clinical safety data does not add anything of further significance to the prescriber.

6. Pharmaceutical Particulars 6.1 List Of Excipients

Benzalkonium chloride

edetate

Sodium chloride

Polysorbate 80

Water for injection

6.2 Incompatibilities

Benzalkonium chloride may be deposited in and is known to discolour soft contact lenses. These lenses should therefore be removed before instillation of the eye drops and not reinserted earlier than 15 minutes after use.

6.3 Shelf Life

Unopened: 24 months

Opened: 1 month

6.4 Special Precautions For Storage

Do not store above 30oC. Protect from direct sunlight.

To avoid contamination do not touch dropper tip to any surface

6.5 Nature And Contents Of Container

The container is a bottle of low density polyethylene (LDPE) with a polystyrene spiked cap closure which contains 13.5ml of Sodium Cromoglicate 2% w/v Eye Drops solution.

6.6 Special Precautions For Disposal And Other Handling

No special instructions.

Administrative Data 7. Marketing Authorisation Holder

FDC International Ltd

Unit 6 Fulcrum 1

Solent Way

Whiteley

Fareham

Hants

PO15 7FE

United Kingdom

8. Marketing Authorisation Number(S)

PL 15872/0010

9. Date Of First Authorisation/Renewal Of The Authorisation

16/05/2007

10. Date Of Revision Of The Text

17 June 2009

Read More:

Ammonium Chloride

Ammonium Chloride
Injection, USP

100 mEq (5 mEq/mL)

CONCENTRATED SOLUTION —

FOR USE ONLY AFTER DILUTION

IN SODIUM CHLORIDE INJECTION.

Plastic Vial

Rx only

Ammonium Chloride Description

Ammonium Chloride Injection, USP, 100 mEq, is a sterile, nonpyrogenic solution of Ammonium Chloride (NH4Cl) in water for injection administered (after dilution) by the intravenous route. Each mL contains 267.5 mg of Ammonium Chloride 5 mEq of ammonium and 5 mEq of chloride) and edetate disodium (anhydrous) 2 mg added as a stabilizer. pH 4.4 (4.0 to 6.0). May contain hydrochloric acid for pH adjustment. 10 mOsmol/mL (calc.). It is intended to be used only after dilution in a larger volume of isotonic (0.9%) sodium chloride injection.

The solution contains no bacteriostat, antimicrobial agent or added buffer (except for pH adjustment) and is intended only for dilution as a single-dose additive. When smaller doses are required the unused portion should be discarded with the entire additive unit.

Ammonium Chloride Injection, USP is an electrolyte replenisher and systemic acidifier.

Ammonium Chloride, USP is chemically designated NH4Cl, colorless crystals or white granular powder freely soluble in water.

The semi-rigid vial is fabricated from a specially formulated polyolefin. It is a copolymer of ethylene and propylene. The safety of the plastic has been confirmed by tests in animals according to USP biological standards for plastic containers. The container requires no vapor barrier to maintain the proper drug concentration.

Ammonium Chloride - Clinical Pharmacology

The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium (Na+) to combine with fixed anions in maintaining acid-base balance, especially as a homeostatic compensatory mechanism in metabolic acidosis.

When a loss of hydrogen ions (H+) occurs and serum chloride (Cl?) decreases, sodium is made available for combination with bicarbonate (HCO3?). This creates an excess of sodium bicarbonate (NaHCO3) which leads to a rise in blood pH and a state of metabolic alkalosis.

The therapeutic effects of Ammonium Chloride depend upon the ability of the kidney to utilize ammonia in the excretion of an excess of fixed anions and the conversion of ammonia to urea by the liver, thereby liberating hydrogen (H+) and chloride (Cl?) ions into the extracellular fluid.

Indications and Usage for Ammonium Chloride

Ammonium Chloride Injection, USP, after dilution in isotonic sodium chloride injection, may be indicated in the treatment of patients with (1) hypochloremic states and (2) metabolic alkalosis.

Contraindications

Ammonium Chloride is contraindicated in patients with severe impairment of renal or hepatic function.

Ammonium Chloride should not be administered when metabolic alkalosis due to vomiting of hydrochloric acid is accompanied by loss of sodium (excretion of sodium bicarbonate in the urine).

Precautions

Patients receiving Ammonium Chloride should be constantly observed for symptoms of ammonia toxicity (pallor, sweating, retching, irregular breathing, bradycardia, cardiac arrhythmias, local and general twitching, tonic convulsions and coma).

It should be used with caution in patients with high total CO2 and buffer base secondary to primary respiratory acidosis.

Intravenous administration should be slow to avoid local irritation and toxic effects.

When exposed to low temperatures, concentrated solutions of Ammonium Chloride may crystallize. If crystals are observed, the vial should be warmed to room temperature in a water bath prior to use.

Do not administer unless the solution is clear and seal is intact. Discard unused portion.

Pregnancy Category C:

Animal reproduction studies have not been conducted with Ammonium Chloride. It is also not known whether Ammonium Chloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Ammonium Chloride should be given to a pregnant woman only if clearly needed.

Adverse Reactions

Rapid intravenous administration of Ammonium Chloride may be accompanied by pain or irritation at the site of injection or along the venous route.

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia (from large volume diluent).

If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.

Overdosage

Overdosage of Ammonium Chloride has resulted in a serious degree of metabolic acidosis, disorientation, confusion and coma. Should metabolic acidosis occur following overdosage, the administration of an alkalinizing solution such as sodium bicarbonate or sodium lactate will serve to correct the acidosis.

Ammonium Chloride Dosage and Administration

Ammonium Chloride Injection, USP is administered intravenously and must be diluted before use. Solutions for intravenous infusion should not exceed a concentration of 1% to 2% of Ammonium Chloride.

Dosage is dependent upon the condition and tolerance of the patient. It is recommended that the contents of one to two vials (100 to 200 mEq) be added to 500 or 1000 mL of isotonic (0.9%) sodium chloride injection. The rate of intravenous infusion should not exceed 5 mL per minute in adults (approximately 3 hours for infusion of 1000 mL). Dosage should be monitored by repeated serum bicarbonate determinations.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.

How is Ammonium Chloride Supplied

Ammonium Chloride Injection, USP, is supplied in 20 mL single-dose plastic Fliptop Containers (NDC 0409-6043-01).

Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.]

Caution: Federal (USA) law prohibits dispensing without prescription.

Revised: December, 2009

Printed in USA

EN-2340

Hospira, Inc., Lake Forest, IL 60045 USA

RL-0386

 

Ammonium Chloride 
Ammonium Chloride  injection, solution, concentrate Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0409-6043 Route of Administration INTRAVENOUS DEA Schedule      Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength Ammonium Chloride (AMMONIUM CATION and CHLORIDE ION) Ammonium Chloride 267.5 mg  in 1 mL Inactive Ingredients Ingredient Name Strength EDETATE DISODIUM ANHYDROUS 2 mg  in 1 mL HYDROCHLORIC ACID   WATER   Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains          Packaging # NDC Package Description Multilevel Packaging 1 0409-6043-01 25 VIAL In 1 TRAY contains a VIAL, SINGLE-DOSE 1 20 mL In 1 VIAL, SINGLE-DOSE This package is contained within the TRAY (0409-6043-01)
Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date ANDA ANDA088366 05/06/2011
Labeler - Hospira, Inc. (141588017) Revised: 08/2011Hospira, Inc. More Ammonium Chloride resources Ammonium Chloride Side Effects (in more detail) Ammonium Chloride Drug Interactions Ammonium Chloride Support Group 0 Reviews for Ammonium Chloride - Add your own review/rating Compare Ammonium Chloride with other medications Alkalosis

Read More:

Diuretics

Diuretics are drugs that increase the volume of urine produced by promoting the excretion of salt and water from the kidneys. There are several types of diuretics, each working in a distinct way.

Loop diuretics prevent re-absorption of sodium and chloride ions in the Loop of Henle. Thiazide diuretics inhibit sodium re-absorption at the beginning of the distal convoluted tubules. Potassium sparing diuretics prevent excessive loss of potassium at the distal convoluted tubules.

Diuretics are used to reduce the edema caused due to salt and water retention in disorders of the heart, kidneys, liver or lungs. They are used commonly in treatment of hypertension.

See also carbonic anhydrase inhibitors loop diuretics miscellaneous diuretics potassium-sparing diuretics thiazide diuretics Drug List:

Read More:

Hypercare topical

Generic Name: aluminum chloride hexahydrate (topical) (al LOO min um KLOR ide hex a HYD rayt TOP ik al)
Brand Names: Drysol, Hypercare, Xerac AC

What is aluminum chloride hexahydrate?

Aluminum chloride hexahydrate is used to treat excessive sweating, also called hyperhidrosis.

Aluminum chloride hexahydrate may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about aluminum chloride hexahydrate?

Use this medication exactly as it was prescribed for you. Do not use it in larger amounts or for longer than recommended by your doctor.

This medicine is for use only on your skin. Avoid getting it in your eyes, mouth, and nose, or on your lips. If it does get into any of these areas, wash with water. Do not use aluminum chloride hexahydrate topical on irritated or broken skin. Do not use the medicine on skin that has recently been shaved. Also avoid using this medication on open wounds. Do not apply any other deodorants or antiperspirants while you are using aluminum chloride hexahydrate.

This medication can stain certain types of fabric or metals that it comes in contact with. Avoid getting the medicine on surfaces you do not want to stain.

What should I discuss with my health care provider before using aluminum chloride hexahydrate? FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether aluminum chloride hexahydrate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How should I use aluminum chloride hexahydrate?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor.

Apply this medication only to completely dry skin. You may need to blow-dry the skin with a hair dryer before applying the medicine.

For best results, apply this medication only at bedtime, when you are less likely to sweat. You will need to leave the medicine on your skin for 6 to 8 hours after application.

To use on the underarms: Apply the medication evenly and allow it to dry. Use a hair dryer on a cool setting to dry the skin if needed. Leave a thin film of the medication on the skin. Wear a tee-shirt or short-sleeved nightgown to bed to keep the medicine from rubbing off onto your bed linens.

To use on the hands or feet: Apply the medication evenly and allow it to dry. Use a hair dryer on a cool setting to dry the skin if needed. Leave a thin film of the medication on the skin. Wrap your hands or feet in plastic wrap and cover with cotton gloves or socks. Leave the gloves or socks on while you sleep.

To use on the scalp: Apply the medication evenly and allow it to dry. Use a hair dryer on a cool setting to dry the skin if needed. Leave a thin film of the medication on the skin. Wear a plastic shower cap to bed to keep the medicine from rubbing off onto your bed linens.

The morning after you apply this medicine, remove your clothing or the plastic covering from the treated skin areas. Throw the plastic wrap away and do not reuse it. Rinse out the plastic shower cap with water and allow it to dry completely before using again.

Wash or shampoo the treated skin areas thoroughly, and towel dry.

Repeat the application of aluminum chloride hexahydrate for 2 or 3 more nights in a row, until you get the desired results of reduced sweating. Using the medication one or two times per week thereafter may be enough to keep your condition under control.

Store this medication at room temperature away from heat or open flame. Aluminum chloride hexahydrate contains alcohol and is flammable.

This medicine will evaporate quickly when exposed to air. Keep the bottle tightly closed when you are not using the medicine.

What happens if I miss a dose?

Since aluminum chloride hexahydrate is used as needed, you may not be on a dosing schedule. If you are using the medication regularly and you miss a dose, wait until the following night and use the medicine at bedtime. Aluminum chloride hexahydrate may not be as effective if you use it during the day while you are awake.

What happens if I overdose? Seek emergency medical attention if you think you have used too much of this medicine. An overdose of aluminum chloride hexahydrate applied to the skin is not expected to produce life-threatening symptoms. What should I avoid while using aluminum chloride hexahydrate? This medicine is for use only on your skin. Avoid getting it in your eyes, mouth, and nose, or on your lips. If it does get into any of these areas, wash with water. Do not use aluminum chloride hexahydrate topical on irritated or broken skin. Do not use the medicine on skin that has recently been shaved. Also avoid using this medication on open wounds. Do not apply any other deodorants or antiperspirants while you are using aluminum chloride hexahydrate.

This medication can stain certain types of fabric or metals that it comes in contact with. Avoid getting the medicine on surfaces you do not want to stain.

Aluminum chloride hexahydrate side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any stinging, burning, redness, or swelling of treated skin areas.

Other less serious side effects are more likely to occur, such as tingling or itching of the treated skin.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect aluminum chloride hexahydrate?

There may be other drugs that can affect aluminum chloride hexahydrate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Hypercare resources Hypercare Use in Pregnancy & Breastfeeding Hypercare Support Group 109 Reviews for Hypercare - Add your own review/rating Compare Hypercare with other medications Hyperhidrosis Where can I get more information? Your pharmacist has more information about aluminum chloride hexahydrate written for health professionals that you may read.

Read More:

Anbesol Teething Gel

1. Name Of The Medicinal Product

Anbesol Teething Gel

2. Qualitative And Quantitative Composition

Lidocaine hydrochloride

1.0%w/w

Chlorocresol

0.1%w/w

Cetylpyridinium chloride

0.02%w/w

3. Pharmaceutical Form

Gel for oral administration.

4. Clinical Particulars 4.1 Therapeutic Indications

For the temporary relief of pain caused by recurrent mouth ulcers, denture irritation and teething.

4.2 Posology And Method Of Administration

Adults, children and the elderly: Apply a small amount to the affected area with a clean fingertip. Two applications immediately will normally be sufficient to obtain pain relief. Use up to four times a day.

Babies teething: Apply a small amount to the affected area with a clean fingertip. Use up to four times a day.

4.3 Contraindications

In patients with a known history of hypersensitivity or allergic type reactions to any of the constituents of the product.

4.4 Special Warnings And Precautions For Use

The following statements will appear on the packaging:

If symptoms persist for more than 7 days, consult your doctor or dentist.

Keep all medicines out of the reach of children.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

None known.

4.6 Pregnancy And Lactation

No special precautions required.

4.7 Effects On Ability To Drive And Use Machines

None known.

4.8 Undesirable Effects

There have been reports of non-specific ulceration following oral cetylpyridinium chloride therapy.

4.9 Overdose

Overdose is extremely unlikely considering the small size of the tube used for sale.

5. Pharmacological Properties 5.1 Pharmacodynamic Properties

Lidocaine is a local anaesthetic of the amide type which acts by reversible inhibition of nerve impulse generation and transmission.

Chlorocresol: Chlorocresol has a disinfectant action.

Cetylpyridinium chloride: Cetylpyridinium chloride has a disinfectant action.

5.2 Pharmacokinetic Properties

Lidocaine hydrochloride

Absorption and fate: Lidocaine is readily absorbed from mucous membranes and through damaged skin. Lidocaine undergoes first-pass metabolism in the liver and about 90% is dealkylated to form monoethylglycinexylidide and glycinexylidide. Further metabolism occurs and the metabolites are excreted in the urine with less than 10% as unchanged lidocaine.

Chlorocresol

Absorption: There is no significant absorption of chlorocresol through the skin or mucous membranes.

Cetylpyridinium chloride

Absorption: There is no significant absorption of cetylpyridinium chloride through the skin or mucous membranes.

5.3 Preclinical Safety Data

The active ingredients in Anbesol Teething Gel have a well established safety record.

6. Pharmaceutical Particulars 6.1 List Of Excipients

Alcohol 96%

Glycerin

Clove Oil

Sodium Saccharin

Hydroxypropyl Cellulose

Ponceau 4R (E124)

Purified Water

6.2 Incompatibilities

None known.

6.3 Shelf Life

36 months unopened.

6.4 Special Precautions For Storage

Store at a temperature not exceeding 25°C.

6.5 Nature And Contents Of Container

Membrane sealed lacquered aluminium tubes fitted with plastic caps containing 10g gel.

6.6 Special Precautions For Disposal And Other Handling

None.

7. Marketing Authorisation Holder

Alliance Pharmaceuticals Limited

Avonbridge House

Bath Road

Chippenham

Wiltshire

SN15 2BB

UK

8. Marketing Authorisation Number(S)

PL 16853/0126

9. Date Of First Authorisation/Renewal Of The Authorisation

31/01/06

10. Date Of Revision Of The Text

29th July 2011

Read More:

Myasthenia Gravis Medications

Definition of Myasthenia Gravis: Myasthenia gravis is a neuromuscular disorder characterized by variable weakness of voluntary muscles, which often improves with rest and worsens with activity. The condition is caused by an abnormal immune response.

Drugs associated with Myasthenia Gravis

The following drugs and medications are in some way related to, or used in the treatment of Myasthenia Gravis. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

Learn more about Myasthenia Gravis

Micromedex Care Notes:

Myasthenia Gravis

Medical Encyclopedia:

Myasthenia gravis

Harvard Health Guide:

Symptoms and treatment for Myasthenia Gravis
Drug List: Mestinon Mestinon-Timespan Mytelase Mytelase-Chloride Prostigmin Prostigmin-Bromide Regonol Soliris

Read More:

Rinstead Sugar Free Pastilles

1. Name Of The Medicinal Product

Rinstead Sugar Free Pastilles

2. Qualitative And Quantitative Composition

Menthol BP 0.033% w/w

Cetylpyridinium chloride BP 0.128% w/w

3. Pharmaceutical Form

Pastille.

4. Clinical Particulars 4.1 Therapeutic Indications

For the temporary relief of pain and discomfort from recurrent mouth ulcers and denture sore spots.

4.2 Posology And Method Of Administration

Adults and children over 12 years:

Allow one pastille to dissolve slowly in the mouth about every two hours.

4.3 Contraindications

Hypersensitivity to cetylpyridinium chloride or menthol or to any component of the formulation.

4.4 Special Warnings And Precautions For Use

If symptoms persist, a physician or dentist should be consulted.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

None known

4.6 Pregnancy And Lactation

The safety of Rinstead Sugar Free Pastilles in pregnancy and lactation has not been established. Therefore, this product should only be used in pregnancy when considered essential by a physician.

4.7 Effects On Ability To Drive And Use Machines

None known.

4.8 Undesirable Effects

Sensitisation to the product is a possible undesirable effect.

4.9 Overdose

If overdose is suspected, this should be treated symptomatically with gastric lavage and supportive therapy, if indicated.

5. Pharmacological Properties 5.1 Pharmacodynamic Properties

Menthol, applied locally in low concentrations, provides a soothing effect.

Cetylpyridinium chloride is an antiseptic, active against a wide spectrum of micro-organisms.

5.2 Pharmacokinetic Properties

Menthol is excreted in the urine and bile as a glucuronide.

Cetylpyridinium chloride is poorly absorbed and is excreted mainly via the faeces.

5.3 Preclinical Safety Data

Not applicable.

6. Pharmaceutical Particulars 6.1 List Of Excipients

Tartaric acid

Amaranth, Rinstead Oils

Sodium ricinoleate (50% sln)

Acesulfame potassium

Acacia gum

Sorbitol

Silicone Antifoam

Vegetable Oil

Beeswax

Water

6.2 Incompatibilities

None known

6.3 Shelf Life

24 months

6.4 Special Precautions For Storage

Store below 25°C

6.5 Nature And Contents Of Container

Aluminium foil/clear PVC blister strips contained in a cardboard carton. Pack sizes of 12, 24, 30, 36 and 48 pastilles.

6.6 Special Precautions For Disposal And Other Handling

Not applicable.

7. Marketing Authorisation Holder

Merck Sharp & Dohme Limited

Hertford Road

Hoddesdon

Hertfordshire

EN11 9BU

UK

8. Marketing Authorisation Number(S)

PL 00025/0586

9. Date Of First Authorisation/Renewal Of The Authorisation

16 April 1996 / 16 April 2001

10. Date Of Revision Of The Text

22 January 2011

11. LEGAL CATEGORY

GSL

© Merck Sharp & Dohme Limited 2011. All rights reserved.

Rinstead SFP/01-11/02

Read More:

Potassium Chloride Liquid

Pronunciation: po-TAS-ee-um KLOR-ide
Generic Name: Potassium Chloride
Brand Name: Examples include Kaon and Rum-K
Potassium Chloride Liquid is used for:

Treating or preventing low potassium blood levels when the amount of potassium in the diet is inadequate. Low potassium levels may also be caused by some diseases, severe or prolonged vomiting or diarrhea, or certain medicines (eg, diuretics). Symptoms of low potassium levels include weakness, fatigue, or weakening of reflexes.

Potassium Chloride Liquid is an electrolyte that is needed for normal functioning of cells, nerve conduction, muscle contraction, kidney function, and acid-base balance.

Do NOT use Potassium Chloride Liquid if: you are allergic to any ingredient in Potassium Chloride Liquid you have a high potassium level you are taking a potassium-sparing diuretic (eg, triamterene)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Potassium Chloride Liquid:

Some medical conditions may interact with Potassium Chloride Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have a high acidity of your body fluids (acidosis), adrenal gland problems, diarrhea, kidney problems, or severe burns if you are dehydrated

Some MEDICINES MAY INTERACT with Potassium Chloride Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

Aldosterone blockers (eg, spironolactone), angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), or potassium-sparing diuretics (eg, triamterene) because the risk of high blood potassium levels may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Potassium Chloride Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Potassium Chloride Liquid:

Use Potassium Chloride Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Potassium Chloride Liquid may cause stomach upset. Take Potassium Chloride Liquid by mouth with food or after meals. The liquid must be diluted before using. The package label will advise the minimum amount (eg, 4 oz) of cold water, juice, or other beverage to mix with the liquid. After thoroughly mixing, drink slowly over a 5- to 10-minute period. Do not lie down for 30 minutes after taking Potassium Chloride Liquid. If you miss a dose of Potassium Chloride Liquid, take it if you remember within 2 hours. If it is more than 2 hours since your missed dose, skip it and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Potassium Chloride Liquid.

Important safety information: Check with your doctor before you use a salt substitute or a product that has potassium in it. Too much or too little potassium can adversely affect the heart. Be sure that your doctor and pharmacist are aware of any heart medications you are taking. This product may contain tartrazine dye (FD&C Yellow No. 5). This may cause an allergic reaction in some patients. If you have ever had an allergic reaction to tartrazine, ask your pharmacist if your product has tartrazine in it. Lab tests, including blood electrolytes and kidney function, may be performed while you use Potassium Chloride Liquid. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Use Potassium Chloride Liquid with caution in the ELDERLY; they may be more sensitive to its effects. Potassium Chloride Liquid should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Potassium Chloride Liquid while you are pregnant. It is not known if Potassium Chloride Liquid is found in breast milk. If you are or will be breast-feeding while you use Potassium Chloride Liquid, check with your doctor. Discuss any possible risks to your baby. Possible side effects of Potassium Chloride Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal skin sensation; confusion; diarrhea; listlessness; nausea; stomach discomfort; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal heartbeat; black, tarry stools; chest pain; heaviness in the legs; indigestion; irregular heartbeat; severe vomiting; stomach pain; tingling in the hands and feet; unusual tiredness or weakness; vomit that looks like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Potassium Chloride side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include chest pain; fast, slow, or irregular heartbeat; limp muscles; listlessness; muscle weakness or paralysis; slow or difficult breathing.

Proper storage of Potassium Chloride Liquid:

Store Potassium Chloride Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly-closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Potassium Chloride Liquid out of the reach of children and away from pets.

General information: If you have any questions about Potassium Chloride Liquid, please talk with your doctor, pharmacist, or other health care provider. Potassium Chloride Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Potassium Chloride Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012 Database Edition 12.1.1.002 Copyright © 2012 Wolters Kluwer Health, Inc. More Potassium Chloride resources Potassium Chloride Side Effects (in more detail)Potassium Chloride Use in Pregnancy & BreastfeedingDrug ImagesPotassium Chloride Drug InteractionsPotassium Chloride Support Group5 Reviews for Potassium Chloride - Add your own review/rating Compare Potassium Chloride with other medications HypokalemiaPrevention of Hypokalemia

Read More:

Potassium Chloride Liquid

---

Related Posts sodium chloride:

• Sodium Chloride Irrigant
• Sodium Chloride Injection 23.4
• Sodium Chloride Irrigation
• magnesium chloride
• Potassium Chloride
• Ammonium Chloride
• Mytelase Chloride
• Strontium Chloride SR 89
• Magnesium Chloride Injection
• Myotonine 25 mg Bethanechol Chloride